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Entries with tag nanomedicine .

Nanomedicine project applications sought for Technology Advisory Board review

If you are leading an innovative project based in nanomedicine, ETP-Nanomedicine is encouraging project applications for review by its Technology Advisory Board (TAB) .   Projects will be reviewed by the TAB and those that are succesful will be given access to invaluable industry advice.   The cut-off date to participate to the next TAB-in sessions is 8 May. ...
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Google X Reveals Nano Pills To Fight Cancerous Cells

Detecting cancer could be as easy as popping a pill in the near future. Google’s head of life sciences, Andrew Conrad, took to the stage at the Wall Street Journal Digital conference to reveal that the tech giant’s secretive Google[x] lab has been working on a wearable device that couples with nanotechnology to detect disease within the body. “We’re passionate about switching from...
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Researchers pioneer world’s first HIV/AIDS nanomedicines

Scientists at the University of Liverpool are leading a £1.65 million project to produce and test the first nanomedicines for treating HIV/AIDS. The research project, funded by the Engineering and Physical Sciences Research Council (EPSRC), aims to produce cheaper, more effective medicines which have fewer side effects and are easier to give to newborns and children. ...
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Biomimetic polymer synthesis enhances structure control

A new biomimetic approach to synthesising polymers will offer unprecedented control over the final polymer structure and yield advances in nanomedicine, researchers say.   In a University of Warwick-led study published in the journal  Nature Chemistry , researchers from the UK (Prof Rachel O’Reilly, Dr Ronan McHale, and Joseph Patterson of the University...
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Critical Pharma and University of Nottingham to develop nano-enabled nasal spray for osteoporosis

Critical Pharmaceuticals, an emerging biotechnology company, and The University of Nottingham today announce a £545,000 collaboration to develop a nano-enabled intranasal formulation of teriparatide for the treatment of osteoporosis. Osteoporosis affects an estimated 75 million people in Europe, US and Japan with more than 180,000 patients suffer fragility fractures in the UK alone...
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System to deliver organ transplant drug- without harmful side effects

A new system for delivering a drug to organ transplant patients, which could avoid the risk of harmful side effects, is being developed by scientists at Strathclyde.   The drug, cyclosporine (CsA), is widely used in transplant operations and helps prevent the patient’s body rejecting the organ  but it can cause adverse drug reactions, of which the most serious...
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Researchers develop "smart" nanotherapeutics that deliver drugs directly to pancreas

A research collaboration has developed "smart" injectable nanotherapeutics that can be programmed to selectively deliver drugs to the cells of the pancreas. Although this nanotechnology will need significant additional testing and development before being ready for clinical use, it could potentially improve treatment for Type I diabetes by increasing therapeutic efficacy and...
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Strategic initiative focused on partnering/licensing of innovative diabetes therapies

MonoSol Rx LLC, the developer of PharmFilm® drug delivery technology, and Midatech Ltd., the developer of MidaForm™ nanoparticle excipients and a global leader and center of excellence for the design, development, synthesis and manufacture of nanomedicines, today announced the launch of their strategic joint venture, MidaSol Therapeutics LP. The launch will focus on the...
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Midatech secures £6.3 million financing to strengthen product development portfolio

Midatech Ltd., a global leader for the design, development, synthesis and manufacture of nanomedicines, announced today it has raised £6.3 million through a private investment round.   This financing will be used to strengthen and diversify Midatech’s product development portfolio, especially in oncology. It will be used to support clinical development of...
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Nanoparticles help researchers deliver steroids to retina

Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, the Mayo Clinic and Johns Hopkins Medicine shows that steroids attached to the dendrimers targeted the damage-causing cells associated with neuroinflammation,...
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DNA damage across a cellular barrier depends on barrier thickness

The use of nanoparticles in medicine is ever increasing and it is important to understand the effects these particles might have on human tissues and health in general. Scientists have shown that signalling molecules that damage the DNA of cells grown underneath a barrier are transmitted only when the barrier is more than one layer thick and DNA damage and cytokine release is signalled...
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Selecta Biosciences initiates Phase 1 Clinical Study of SEL-068, a synthetic nicotine vaccine for smoking cessation and relapse prevention

Selecta Biosciences Inc a biopharmaceutical company developing a new class of synthetic vaccines and immunotherapies, today announced that it has initiated a Phase 1 clinical trial to assess the safety, tolerability and pharmacodynamic profile of SEL-068, a nicotine vaccine candidate for smoking cessation and relapse prevention. SEL-068 is the first product candidate to enter clinical...
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Tekmira Pharmaceuticals receives approval from FDA to initiate TKM-Ebola Phase 1 Clinical Trial

Tekmira Pharmaceuticals Corporation a leading developer of RNA interference (RNAi) therapeutics, announced today that its Investigational New Drug (IND) application for TKM-Ebola has been approved by the United States Food and Drug Administration (FDA) allowing Tekmira to initiate a Phase 1 clinical trial.   Tekmira is developing TKM-Ebola, a systemically delivered RNAi...
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Quest PharmaTech announces development of second generation photodynamic therapy products for the treatment of cancer based on nanotechnology

Quest PharmaTech Inc a biotechnology company developing and commercializing products for the treatment of cancer, today announced the acceptance for publication of a research paper entitled "Antitumor Efficacy of Photodynamic Therapy Using Novel Nanoformulations of Hypocrellin Photosensitizer SL052", in the Journal of Photochemistry and Photobiology. The paper highlighted the...
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A realistic look at the promises and perils of nanomedicine

Is the emerging field of nanomedicine a breathtaking technological revolution that promises remarkable new ways of diagnosing and treating diseases? Or does it portend the release of dangerous nanoparticles, nanorobots or nanoelectronic devices that will wreak havoc in the body? A new review of more than 500 studies on the topic concludes that neither scenario is likely. It appears in...
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Nanomedicine breakthrough by IBN and IBM named top 10 world changing ideas by Scientific American

A nanoparticle that can destroy drug-resistant bacteria developed by the Institute of Bioengineering and Nanotechnology (IBN), and the IBM Almaden Research Center, has recently been named one of 10 world changing ideas by Scientific American (December 2011) in its Technology Special Report on “World Changing Ideas – 10 New Technologies That Will Make a Difference”. ...
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Midatech receives regulatory approval for clinically testing ultra-small gold nanoparticles

Midatech Ltd., a global leader in the design, development, synthesis and manufacture of nanomedicines, announced today it has received Swissmedic approval to start the First-in-Human clinical trial with insulin-coated gold nanoparticles, which will be coordinated through its Swiss subsidiary PharMida AG.   The trial is designed to assess the safety profile of insulin-coated...
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Hi–tech diabetes aid will send alert text in emergency

A hi-tech diabetes blood glucose monitor is being developed in Wales that will send a text alert to emergency personnel if the patient is in danger of hypoglycaemia attack.   Scientists from Swansea University are collaborating with a number of Welsh technology companies and bringing their combined expertise in areas ranging from nanoelectronics and e-health technologies to...
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Landmark publication reports potential of exosomes as biomarkers for early disease detection using NanoSight’s NTA technology

NanoSight, leading manufacturers of unique nanoparticle characterisation technology, reports the new publication in one of the most cited peer reviewed journals in nanoscience and nanotechnology, NanoMedicine. It has been written by a group of researchers from the Nuffield Department of Obstetrics & Gynaecology, Oxford University.   The rapidly growing field of exosomes...
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Just Add Water and... Treat Brain Cancer? - Freeze-dried gene therapy system avoids virus, potential complications

Researchers have developed a technique that delivers gene therapy into human brain cancer cells using nanoparticles that can be freeze-dried and stored for up to three months prior to use.   The shelf-stable particles may obviate the need for virus-mediated gene therapy, which has been associated with safety concerns. The report appears in the August issue of Biomaterials. ...
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DNA cages 'can survive inside living cells'

Scientists at Oxford University have shown for the first time that molecular cages made from DNA can enter and survive inside living cells. The work, a collaboration between physicists and molecular neuroscientists at Oxford, shows that artificial DNA cages that could be used to carry cargoes of drugs can enter living cells, potentially leading to new methods of drug delivery.   ...
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Gold nanoparticles help earlier diagnosis of liver cancer

A research team has devised a new technique to spot cancerous tumors in the liver as small as 5 millimeters. The technique, using gold nanoparticles, is the first to deploy metal nanoparticles as agents to enhance X-ray scattering of image tumor-like masses. Results are published in in the American Chemical Society journal Nano Letters.   A big obstacle to treatment of liver...
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Glowing Cornell Dots – a potential cancer diagnostic tool set for human trials

The U.S. Food and Drug Administration (FDA) has approved the first clinical trial in humans of a new technology: Cornell Dots, brightly glowing nanoparticles that can light up cancer cells in PET-optical imaging.   A paper describing this new medical technology, “Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma,”...
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Research creates nanoparticles perfectly formed to tackle cancer

Researchers from the University of Hull have discovered a way to load up nanoparticles with large numbers of light-sensitive molecules to create a more effective form of photodynamic therapy (PDT) for treating cancer.   Photodynamic therapy (PDT) uses molecules which, when irradiated with light, cause irreparable damage to cells by creating toxic forms of oxygen, called...
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Quantum sensor tracked in human cells could aid drug discovery

Groundbreaking research has shown a quantum atom has been tracked inside a living human cell and may lead to improvements in the testing and development of new drugs.   Professor Lloyd Hollenberg from the University of Melbourne’s School of Physics who led the research said it is the first time a single atom encased in nanodiamond has been used as a sensor to explore the...
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